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DSIP, 10mg, lyophilized research peptide vial, Eppix Labs
Certificate of Analysis — 10mgCertificate of Analysis for DSIP 10mg
Chemical StructureDSIP chemical structure
Amino Acid SequenceDSIP amino acid chain
Latest COA

DSIP 10mg

Janoshik

Batch DSIP-CA-26F-10

Result2026-07-13
Added2026-08-04
Avg Purity99.623%
Avg Mass11.85 mg
Verify on Janoshik
In StockCognitive
BatchDSIP-CA-26A-01

DSIP

Delta Sleep–Inducing Peptide

DSIP is a peptide frequently examined for its involvement in sleep regulation and circadian rhythm activity in laboratory settings. Research often focuses on its potential influence on stress modulation, recovery cycles, and overall neurological balance in controlled models.

$40.00USD
Purity VerifiedLab TestedSecure
Research Use Only

This product is intended strictly for laboratory research use within the United States. It is not approved by the FDA for the diagnosis, treatment, cure, or prevention of any disease. Not for human or veterinary use.

By purchasing, you confirm the material will be used solely for lawful research purposes in accordance with applicable U.S. federal, state, and local regulations.

DSIP, also known as Delta Sleep–Inducing Peptide, is a synthetic neuropeptide developed for controlled laboratory research. It was originally identified during investigations into sleep-phase regulation and neuroendocrine signaling systems.

In scientific literature, DSIP is studied within experimental models examining circadian-associated pathways, central nervous system signaling frameworks, and stress-related regulatory mechanisms under in vitro and preclinical research conditions.

Purity

Third-party tested for purity, ID, quantity.

Amino Acid Sequence
Amino acid chain diagram
Chemical Structure
Chemical structure diagram
Compound Properties
CAS Number62568-57-4
Molecular FormulaC₃₅H₄₈N₁₀O₁₅
Molecular Weight848.81 g/mol
PubChem CID68816

Overview

DSIP is a short neuropeptide first reported in the 1970s during investigations into delta-wave activity and sleep-associated physiological processes. Following its identification, research expanded into broader neuroendocrine and central nervous system signaling models.

Experimental studies examine DSIP within controlled laboratory frameworks to better understand its interaction with circadian-associated mechanisms and hypothalamic-pituitary regulatory pathways.

History

Delta Sleep–Inducing Peptide was initially isolated during studies focused on sleep physiology and delta-wave modulation. Early investigations centered on its role within central nervous system research models, with later work examining neuroendocrine signaling interactions under controlled conditions.

Over time, DSIP became a recurring subject in laboratory research exploring peptide-based signaling within neurological and regulatory pathway systems.

Key Research Areas

Laboratory investigations into DSIP have explored its interaction with neuroendocrine signaling systems and circadian-related regulatory pathways. Research models evaluate peptide behavior within central nervous system frameworks and stress-response signaling under controlled in vitro and preclinical conditions.

1 of the 4 areas below are addressed directly by a paper cited on this page.

Neuroendocrine signaling pathway models

No paper cited on this page reports on neuroendocrine. This heading marks where DSIP is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.

Circadian and delta-wave research frameworks

Addressed on this page by Monnier 1977, Schoenenberger 1978, Schneider-Helmert 1981. The work appeared in Pflugers Arch and Int J Clin Pharmacol Ther Toxicol. Each is linked to its source record in the references below, so what was measured — and in what system — can be read rather than taken on trust.

  • Monnier, M. et al. (1977) The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide.
  • Schoenenberger, G.A. et al. (1978) The delta EEG (sleep)-inducing peptide (DSIP). XI. Amino-acid analysis, sequence, synthesis and activity of the nonapeptide. Pflugers Arch 376(2):119–129.
  • Schneider-Helmert, D. et al. (1981) Acute and delayed effects of DSIP (delta sleep-inducing peptide) on human sleep behavior. Int J Clin Pharmacol Ther Toxicol 19(8):341–345.

Central nervous system regulatory studies

No paper cited on this page reports on central or nervous. This heading marks where DSIP is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.

Stress-response mechanism investigations

No paper cited on this page reports on stress or response. This heading marks where DSIP is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.

The references section of this page cites 10 primary papers published between 1977 and 2006 — a reasonably developed body of work for a research compound. Every citation is linked to its PubMed or DOI record so it can be read rather than taken on trust, and the summaries above describe what those papers report rather than what the compound is claimed to do.

Research compounds attract claims that outrun their evidence. Below are the ones most often encountered for DSIP, set against what the papers cited on this page actually report. Where the record is thin or contested, that is stated rather than smoothed over.

Also called

DSIP is also referred to as delta sleep peptide, the sleep peptide.

Preclinical only

DSIP is commonly described online in connection with sharper focus, better memory and improved mood. In the research literature the same compound is filed under neuroendocrine signaling pathway models, circadian and delta-wave research frameworks and central nervous system regulatory studies.

The 10 papers cited on this page, published between 1977 and 2006 (1 review) describe laboratory and animal work. None reports a controlled trial in humans. Findings in cell culture or in a rodent model describe what happened in that system; they do not establish that the same occurs in humans, and this compound is not approved for human use.

Nothing above is a statement of what this material does. It is a summary of what has been published and what has not. Eppix Labs supplies research materials only and provides no dosing, administration or protocol guidance.

Verification for DSIP is per lot, not per product. The current 10mg lot DSIP-CA-26F-10 returned 99.623% purity, 11.85 mg measured, 118.5% of the labelled 10 mg, assayed by Janoshik. Those figures are the laboratory's, published in full rather than reduced to a badge.

Purity is half the number. It states what fraction of the material in the vial is DSIP; it says nothing about how much material is in the vial, and a short-filled vial can return a purity result that is entirely accurate. The figure that answers the second question is measured mass against expected content — for DSIP, this lot measured 118.5% of its labelled 10 mg. Both numbers are published for every lot, whichever way they fall.

The lot code printed on the vial matches the code on the certificate for DSIP. Matching the two is what confirms the unit in hand came from the batch that was tested — a certificate not tied to a lot code proves nothing about any particular unit.

Researchers who buy DSIP in the United States through Eppix Labs receive the lot described by the certificate above: the code printed on the vial label is the code on the certificate, and both are searchable on the batch verification page.

Verify a batch code →

Lyophilized storage
−20 °C long-term; stable at room temperature in transit
After reconstitution
2–8 °C
Light
Protect from UV and direct light
Freeze-thaw
Avoid repeated cycles
Vehicle
Bacteriostatic water in most published protocols
Format
Lyophilized powder

DSIP is supplied as lyophilized powder. In the dry state the material is comparatively stable, which is why it ships at ambient temperature without a cold chain; once reconstituted it is a peptide in solution and the handling constraints tighten considerably. At 9 residues it is short enough to be produced by solid-phase synthesis, and the published sequence on this page is what an identity assay is checked against.

Repeated freeze-thaw cycling is the handling error most likely to degrade material of this class, because each cycle concentrates solutes at the ice boundary. Where a protocol calls for the same vial across multiple sessions, the published literature generally describes aliquoting after reconstitution rather than re-freezing the whole volume.

Vials may appear empty on arrival. Lyophilized material collects at the base of the vial and is often not visible until the vial is inspected under direct light.

Reconstitution calculator →

Included
  • 1 × sealed glass vial in the strength selected (10mg / Single Vial, 10mg / 5-Pack, 10mg / 10-Pack available), batch-labelled
  • The batch-linked Certificate of Analysis for the exact lot shipped
  • Discreet outer packaging with no product names on the exterior
  • FedEx, tracked, typically 1–3 business days domestically
Not included
  • Bacteriostatic water or any other reconstitution vehicle
  • Syringes, needles or filters
  • Dosing, administration or protocol guidance of any kind

Reconstitution materials are sourced separately. The reconstitution calculator on this site works out concentrations for a given volume, but it is an arithmetic tool for laboratory record-keeping and not a protocol.

No. Eppix Labs products are supplied exclusively for laboratory research. We do not provide dosing, administration, or usage guidance.

Each vial contains 12mg of lyophilized DSIP. Independent third-party testing verifies purity, identity, and net content per batch.

The vial contains only the lyophilized peptide. Any laboratory materials required for reconstitution or experimental procedures must be sourced separately.

Duration depends entirely on research protocol, storage conditions, and laboratory application.

Monnier, M. et al.(1977)

The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide.

PubMed
Schoenenberger, G.A. et al.(1978)

The delta EEG (sleep)-inducing peptide (DSIP). XI. Amino-acid analysis, sequence, synthesis and activity of the nonapeptide. Pflugers Arch 376(2):119–129.

PubMed
Schneider-Helmert, D. et al.(1981)

Acute and delayed effects of DSIP (delta sleep-inducing peptide) on human sleep behavior. Int J Clin Pharmacol Ther Toxicol 19(8):341–345.

PubMed
Schneider-Helmert, D. & Schoenenberger, G.A.(1981)

The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep.

PubMed
Graf, M.V. & Kastin, A.J.(1984)

Delta-sleep-inducing peptide (DSIP): a review.

PubMed
Schoenenberger, G.A.(1984)

Characterization, properties and multivariate functions of delta-sleep-inducing peptide (DSIP).

PubMed
Graf, M.V. & Kastin, A.J.(1986)

Delta-sleep-inducing peptide (DSIP): an update.

PubMed
Schneider-Helmert, D. et al.(1987)

Effects of delta-sleep-inducing peptide on 24-hour sleep-wake behaviour in severe chronic insomnia. Eur Neurol 27(2):120–129.

PubMed
Pollard, B.J. & Pomfrett, C.J.D.(2001)

Delta sleep-inducing peptide.

PubMed
Kovalzon, V.M.(2006)

Delta sleep-inducing peptide (DSIP): a still unresolved riddle.

PubMed

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