Growth Hormone
Growth Hormone Research Peptides
Two mechanisms sit side by side in this category and are routinely conflated. Sermorelin, tesamorelin and CJC-1295 are GHRH analogues acting at the growth-hormone-releasing hormone receptor. Ipamorelin and MK-677 are secretagogues acting at the ghrelin receptor, GHS-R1a. They reach a related endpoint through unrelated receptors, which is precisely why the published research examines them in combination.
IGF-1 LR3 belongs to neither group. It is a modified insulin-like growth factor with reduced binding-protein affinity, studied downstream of growth hormone rather than upstream of it.
Structural identity is published for everything here: full amino acid sequence where the compound is a peptide, plus CAS number, molecular formula and molar mass. Those identifiers are what a mass-spectrometry identity check is read against, and they are worth having before evaluating any supplier's certificate.
Each lot is independently assayed before release, with measured purity and measured mass against the labelled content published per batch and linked to the lot code printed on the vial. Supplied strictly as laboratory research materials, shipped domestically within the United States.
In this category: Ipamorelin · CJC-1295 · Sermorelin · Tesamorelin · IGF-1 LR3
What to check before buying growth hormone compounds
Purity is half the number. A purity figure tells you what fraction of the powder in the vial is the compound on the label — it tells you nothing about how much powder is in the vial. A lot can assay at 99.8% purity and still be short against its labelled content.
Both numbers are published for every batch here: purity from HPLC, and measured mass against expected content. Match the batch code printed on the vial to the certificate before you rely on either.
Growth Hormone research peptides — common questions
- GHRH analogue or secretagogue — what is the difference?
- Different receptors. Sermorelin, CJC-1295 and tesamorelin are analogues of growth hormone-releasing hormone and act at the GHRH receptor. Ipamorelin is a ghrelin receptor agonist, an independent pathway. The published work frequently studies one of each together, which is also why the blends in this catalogue pair them.
- What does the DAC in CJC-1295 refer to?
- Drug Affinity Complex — a modification that binds the peptide to serum albumin and substantially extends its circulating half-life. The with-DAC and no-DAC forms therefore behave as different compounds in the literature. This store lists the no-DAC form, also written as modified GRF (1-29).
- Where does IGF-1 LR3 fit in?
- Downstream. IGF-1 is the mediator through which much of growth hormone activity is described, and the LR3 variant carries an amino-acid substitution plus an N-terminal extension that reduce binding to IGF-binding proteins. It is in this category because the literature treats the whole axis as one subject.
- What testing is done before a lot ships?
- Identity by mass spectrometry and purity by reversed-phase HPLC, both at an independent laboratory, with measured content reported against the labelled amount. Results are published as measured — a lot that comes in under label is published under label, because a supplier that posts only its best numbers has answered the easy question.
