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Mitochondrial-Derived Peptide
Also known as HN, 24-residue mitochondrial ORF peptide
Humanin is a 24-residue peptide encoded within the mitochondrial genome, studied in research on cytoprotection and apoptosis-related signaling.
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This product is intended strictly for laboratory research use within Canada. It is not approved by Health Canada for the diagnosis, treatment, cure, or prevention of any disease. Not for human or veterinary use.
By purchasing, you confirm the material will be used solely for lawful research purposes in accordance with applicable Canadian regulations.
Humanin is a 24-residue peptide encoded within the mitochondrial genome, studied in research on cytoprotection and apoptosis-related signaling.
Experimental models examine its release from mitochondria and its influence on stress-resistance pathways.
Third-party tested for purity, ID, quantity.
Humanin was the first mitochondrial-derived peptide to be described, transcribed from a short open reading frame in the mitochondrial 16S rRNA region. Research has characterized its cytoprotective activity, including suppression of apoptosis and modulation of stress-response signaling in neuronal, cardiac, and metabolic models.
Studies have examined its release by astrocytes, its relationship to lifespan and healthspan endpoints, and its behaviour within the wider mitokine literature alongside MOTS-c.
Humanin was identified in screening work seeking factors that protect neurons from amyloid-beta toxicity, and was subsequently traced to a mitochondrial open reading frame.
That discovery opened the mitochondrial-derived peptide field, with later work characterizing humanin across cardiovascular, reproductive, oncological, and ageing research models.
Research into humanin focuses on mitochondrial-derived peptide signaling and cytoprotection. Frameworks evaluate apoptosis suppression, stress-resistance pathways, synaptic maintenance, and lifespan-related endpoints under controlled in vitro and preclinical conditions.
No. Eppix Labs products are supplied exclusively for laboratory research. We do not provide dosing, administration, or usage guidance.
Each unit contains the labeled quantity of humanin. Independent third-party analysis verifies purity, identity, and net content per batch.
The unit contains only the research compound. Any laboratory materials required for reconstitution or experimental procedures must be sourced separately.
Duration depends entirely on research design, storage conditions, and laboratory protocol.
Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases
PubMedThe emerging role of the mitochondrial-derived peptide humanin in stress resistance
PubMedHumanin, a Mitochondrial-Derived Peptide Released by Astrocytes, Prevents Synapse Loss in Hippocampal Neurons
PubMedThe mitochondrial derived peptide humanin is a regulator of lifespan and healthspan
PubMedMitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseases
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