Epitalon 10mg
Janoshik
Batch EPIT-CA-26G-10
Epitalon
Synthetic Tetrapeptide Research Compound
Epitalon is often investigated for its role in cellular aging pathways, particularly in relation to telomere activity and long-term cellular stability in research models. Studies commonly explore its potential effects on oxidative balance, biological aging processes, and overall cellular function within controlled laboratory settings.
This product is intended strictly for laboratory research use within the United States. It is not approved by the FDA for the diagnosis, treatment, cure, or prevention of any disease. Not for human or veterinary use.
By purchasing, you confirm the material will be used solely for lawful research purposes in accordance with applicable U.S. federal, state, and local regulations.
Epitalon, also known in scientific literature as Epithalon, is a synthetic tetrapeptide composed of alanine–glutamic acid–aspartic acid–glycine (Ala-Glu-Asp-Gly). It is developed for controlled laboratory research involving peptide-mediated regulatory systems.
In experimental models, Epitalon is studied in frameworks examining cellular signaling pathways, telomere-associated research systems, and regulatory peptide interaction mechanisms under in vitro and preclinical research conditions.
Third-party tested for purity, identity, quantity.
Epitalon is a short synthetic peptide evaluated in research focused on regulatory peptide signaling systems and telomere-associated biological frameworks. Experimental studies examine its interaction within cellular signaling environments and peptide-mediated pathway models under controlled laboratory conditions.
Research publications have explored its role in cellular regulatory systems and telomerase-associated research frameworks within structured experimental settings.
Epitalon was developed through investigations into short regulatory peptides derived from pineal gland research. Early experimental work examined its biochemical properties and signaling characteristics in laboratory models.
Subsequent research expanded into studies exploring peptide-mediated regulatory systems and telomere-associated pathway interaction frameworks.
Laboratory investigations into Epitalon have focused on regulatory peptide signaling models and telomere-associated pathway research systems. Research frameworks evaluate peptide interaction within cellular regulatory environments and signaling cascades under controlled in vitro and preclinical conditions.
2 of the 4 areas below are addressed directly by a paper cited on this page.
Regulatory peptide signaling models
Addressed on this page by Araj 2025, Khavinson 2020, Caputi 2019. The work appeared in Int J Mol Sci. Each is linked to its source record in the references below, so what was measured — and in what system — can be read rather than taken on trust.
- Araj, S.K. et al. (2025) — Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties. Int J Mol Sci 26(6):2509.
- Khavinson, V. et al. (2020) — AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism.
- Caputi, S. et al. (2019) — Effect of short peptides on neuronal differentiation of stem cells.
Telomere-associated pathway research
No paper cited on this page reports on telomere or associated. This heading marks where Epitalon is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.
Cellular signaling framework investigations
No paper cited on this page reports on cellular. This heading marks where Epitalon is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.
Short peptide interaction studies
Addressed on this page by Caputi 2019, Araj 2025, Khavinson 2020. The work appeared in Int J Mol Sci. Each is linked to its source record in the references below, so what was measured — and in what system — can be read rather than taken on trust.
- Caputi, S. et al. (2019) — Effect of short peptides on neuronal differentiation of stem cells.
- Araj, S.K. et al. (2025) — Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties. Int J Mol Sci 26(6):2509.
- Khavinson, V. et al. (2020) — AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism.
The references section of this page cites 5 primary papers published between 2017 and 2025 — a limited but non-trivial record. Every citation is linked to its PubMed or DOI record so it can be read rather than taken on trust, and the summaries above describe what those papers report rather than what the compound is claimed to do.
Research compounds attract claims that outrun their evidence. Below are the ones most often encountered for Epitalon, set against what the papers cited on this page actually report. Where the record is thin or contested, that is stated rather than smoothed over.
Epitalon is also referred to as epithalon, epithalamin.
Described as extending lifespan by lengthening telomeres.
Epitalon comes from a Russian research tradition associated with Vladimir Khavinson, and the telomerase-related work sits largely in that body of literature. Much of it is not indexed in English-language databases in a form that permits independent appraisal, and the human longevity claims rest on studies that have not been replicated by independent groups outside that tradition. Reporting how thin and how concentrated that record is matters more here than summarising its conclusions.
Nothing above is a statement of what this material does. It is a summary of what has been published and what has not. Eppix Labs supplies research materials only and provides no dosing, administration or protocol guidance.
Verification for Epitalon is per lot, not per product. The current 10mg lot EPIT-CA-26G-10 returned 98.728% purity, 11.56 mg measured, 115.6% of the labelled 10 mg, assayed by Janoshik. Those figures are the laboratory's, published in full rather than reduced to a badge.
Purity is half the number. It states what fraction of the material in the vial is Epitalon; it says nothing about how much material is in the vial, and a short-filled vial can return a purity result that is entirely accurate. The figure that answers the second question is measured mass against expected content — for Epitalon, this lot measured 115.6% of its labelled 10 mg. Both numbers are published for every lot, whichever way they fall.
The lot code printed on the vial matches the code on the certificate for Epitalon. Matching the two is what confirms the unit in hand came from the batch that was tested — a certificate not tied to a lot code proves nothing about any particular unit.
Researchers who buy Epitalon in the United States through Eppix Labs receive the lot described by the certificate above: the code printed on the vial label is the code on the certificate, and both are searchable on the batch verification page.
- Lyophilized storage
- −20 °C long-term; stable at room temperature in transit
- After reconstitution
- 2–8 °C
- Light
- Protect from UV and direct light
- Freeze-thaw
- Avoid repeated cycles
- Vehicle
- Bacteriostatic water in most published protocols
- Format
- Lyophilized powder
Epitalon is supplied as lyophilized powder. In the dry state the material is comparatively stable, which is why it ships at ambient temperature without a cold chain; once reconstituted it is a peptide in solution and the handling constraints tighten considerably. At 4 residues it is short enough to be produced by solid-phase synthesis, and the published sequence on this page is what an identity assay is checked against.
Repeated freeze-thaw cycling is the handling error most likely to degrade material of this class, because each cycle concentrates solutes at the ice boundary. Where a protocol calls for the same vial across multiple sessions, the published literature generally describes aliquoting after reconstitution rather than re-freezing the whole volume.
Vials may appear empty on arrival. Lyophilized material collects at the base of the vial and is often not visible until the vial is inspected under direct light.
- 1 × sealed glass vial in the strength selected (10mg / Single Vial, 10mg / 5-Pack, 10mg / 10-Pack available), batch-labelled
- The batch-linked Certificate of Analysis for the exact lot shipped
- Discreet outer packaging with no product names on the exterior
- FedEx, tracked, typically 1–3 business days domestically
- Bacteriostatic water or any other reconstitution vehicle
- Syringes, needles or filters
- Dosing, administration or protocol guidance of any kind
Reconstitution materials are sourced separately. The reconstitution calculator on this site works out concentrations for a given volume, but it is an arithmetic tool for laboratory record-keeping and not a protocol.
No. Eppix Labs products are supplied exclusively for laboratory research. We do not provide dosing, administration, or usage guidance.
Each vial contains 10mg of lyophilized Epitalon. Independent third-party testing verifies purity, identity, and net content per batch.
The vial contains only the peptide preparation. Any laboratory materials required for experimental procedures must be sourced separately.
Duration depends entirely on research protocol, storage conditions, and laboratory application.
Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties. Int J Mol Sci 26(6):2509.
PubMedEpitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro.
PubMedAEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism.
PubMedIdentification of Peptide AEDG in the Polypeptide Complex of the Pineal Gland.
PubMedRelated
You May Also Like
Peptide complex studied for cartilage signaling, joint integrity, and connective tissue pathway research
From$49.99
Immune-modulating peptide studied for T-cell signaling and immune system regulatory pathway research
From$54.99
Next-generation GLP receptor agonist studied for metabolic signaling and nutrient partitioning pathways
From$79.99
Dual incretin receptor agonist studied for glucose regulation, metabolic signaling, and weight pathway research
From$39.99