MT-2 10mg
Janoshik
Batch MT2-CA-26F-10
Melanotan II
Melanocortin Receptor Research Peptide
Melanotan II is a synthetic peptide studied in laboratory settings for its interaction with melanocortin receptors and related signaling pathways. Research commonly examines its effects on pigmentation-related mechanisms, receptor activity, and broader melanocortin system responses in controlled experimental models.
This product is intended strictly for laboratory research use within the United States. It is not approved by the FDA for the diagnosis, treatment, cure, or prevention of any disease. Not for human or veterinary use.
By purchasing, you confirm the material will be used solely for lawful research purposes in accordance with applicable U.S. federal, state, and local regulations.
Melanotan II is a synthetic cyclic peptide analogue derived from alpha-melanocyte–stimulating hormone (α-MSH). It is developed for controlled laboratory research involving melanocortin receptor signaling systems.
In scientific literature, Melanotan II is studied in experimental models examining melanocortin receptor interaction, neuroendocrine signaling pathways, and receptor-mediated regulatory mechanisms under in vitro and preclinical research conditions.
Third-party tested for purity, identity, quantity.
Melanotan II is a cyclic melanocortin receptor agonist evaluated in research focused on melanocortin pathway signaling and receptor interaction dynamics. Experimental studies examine its interaction within neuroendocrine regulatory systems and melanocortin-associated signaling frameworks under controlled laboratory conditions.
Research publications have explored its receptor-binding profile and pathway-level signaling characteristics within structured experimental environments.
Melanotan II originated from research into melanocortin receptor agonists derived from α-MSH analogues. Structural modifications led to the development of cyclic peptides designed to enhance receptor interaction properties for experimental study.
Subsequent investigations documented its receptor subtype interaction and signaling behavior in laboratory research models.
Laboratory investigations into Melanotan II have focused on melanocortin receptor activation models and neuroendocrine signaling pathways. Research frameworks evaluate receptor-mediated interaction, melanocortin pathway dynamics, and peptide-associated regulatory systems under controlled in vitro and preclinical conditions.
2 of the 4 areas below are addressed directly by a paper cited on this page.
Melanocortin receptor activation models
Addressed on this page by Eliason 2022, Yue 2023. Each is linked to its source record in the references below, so what was measured — and in what system — can be read rather than taken on trust.
- Eliason, N.L. et al. (2022) — Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food.
- Yue, W.K. et al. (2023) — Targeting Melanocortin Receptors Using SNAr-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates.
Neuroendocrine signaling pathway studies
No paper cited on this page reports on neuroendocrine. This heading marks where Melanotan II is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.
α-MSH analogue research frameworks
No paper cited on this page reports on analogue. This heading marks where Melanotan II is discussed in the category rather than a question the cited literature answers, and it is worth knowing which of these areas has work behind it and which does not.
Receptor subtype interaction investigations
Addressed on this page by Eliason 2022, Yue 2023. Each is linked to its source record in the references below, so what was measured — and in what system — can be read rather than taken on trust.
- Eliason, N.L. et al. (2022) — Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food.
- Yue, W.K. et al. (2023) — Targeting Melanocortin Receptors Using SNAr-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates.
The references section of this page cites 5 primary papers published between 2022 and 2024 — a limited but non-trivial record. Every citation is linked to its PubMed or DOI record so it can be read rather than taken on trust, and the summaries above describe what those papers report rather than what the compound is claimed to do.
Research compounds attract claims that outrun their evidence. Below are the ones most often encountered for Melanotan II, set against what the papers cited on this page actually report. Where the record is thin or contested, that is stated rather than smoothed over.
Melanotan II is also referred to as MT-2, MT2, melanotan 2.
Melanotan II is commonly described online in connection with increased libido and sexual function. In the research literature the same compound is filed under melanocortin receptor activation models, neuroendocrine signaling pathway studies and α-MSH analogue research frameworks.
The 5 papers cited on this page, published between 2022 and 2024 (1 in animal models) describe laboratory and animal work. None reports a controlled trial in humans. Findings in cell culture or in a rodent model describe what happened in that system; they do not establish that the same occurs in humans, and this compound is not approved for human use.
Nothing above is a statement of what this material does. It is a summary of what has been published and what has not. Eppix Labs supplies research materials only and provides no dosing, administration or protocol guidance.
Verification for Melanotan II is per lot, not per product. The current 10mg lot MT2-CA-26F-10 returned 99.887% purity, 11.12 mg measured, 111.2% of the labelled 10 mg, assayed by Janoshik. Those figures are the laboratory's, published in full rather than reduced to a badge.
Purity is half the number. It states what fraction of the material in the vial is Melanotan II; it says nothing about how much material is in the vial, and a short-filled vial can return a purity result that is entirely accurate. The figure that answers the second question is measured mass against expected content — for Melanotan II, this lot measured 111.2% of its labelled 10 mg. Both numbers are published for every lot, whichever way they fall.
The lot code printed on the vial matches the code on the certificate for Melanotan II. Matching the two is what confirms the unit in hand came from the batch that was tested — a certificate not tied to a lot code proves nothing about any particular unit.
Researchers who buy Melanotan II in the United States through Eppix Labs receive the lot described by the certificate above: the code printed on the vial label is the code on the certificate, and both are searchable on the batch verification page.
- Lyophilized storage
- −20 °C long-term; stable at room temperature in transit
- After reconstitution
- 2–8 °C
- Light
- Protect from UV and direct light
- Freeze-thaw
- Avoid repeated cycles
- Vehicle
- Bacteriostatic water in most published protocols
- Format
- Lyophilized powder
Melanotan II is supplied as lyophilized powder. In the dry state the material is comparatively stable, which is why it ships at ambient temperature without a cold chain; once reconstituted it is a peptide in solution and the handling constraints tighten considerably. At 7 residues it is short enough to be produced by solid-phase synthesis, and the published sequence on this page is what an identity assay is checked against.
Repeated freeze-thaw cycling is the handling error most likely to degrade material of this class, because each cycle concentrates solutes at the ice boundary. Where a protocol calls for the same vial across multiple sessions, the published literature generally describes aliquoting after reconstitution rather than re-freezing the whole volume.
Vials may appear empty on arrival. Lyophilized material collects at the base of the vial and is often not visible until the vial is inspected under direct light.
- 1 × sealed glass vial in the strength selected (10mg / Single Vial, 10mg / 5-Pack, 10mg / 10-Pack available), batch-labelled
- The batch-linked Certificate of Analysis for the exact lot shipped
- Discreet outer packaging with no product names on the exterior
- FedEx, tracked, typically 1–3 business days domestically
- Bacteriostatic water or any other reconstitution vehicle
- Syringes, needles or filters
- Dosing, administration or protocol guidance of any kind
Reconstitution materials are sourced separately. The reconstitution calculator on this site works out concentrations for a given volume, but it is an arithmetic tool for laboratory record-keeping and not a protocol.
No. Eppix Labs products are supplied exclusively for laboratory research. We do not provide dosing, administration, or usage guidance.
Each vial contains 10mg of lyophilized Melanotan II. Independent third-party testing verifies purity, identity, and net content per batch.
The vial contains only the peptide preparation. Any laboratory materials required for experimental procedures must be sourced separately.
Duration depends entirely on research protocol, storage conditions, and laboratory application.
Therapeutic Strategies Against Metabolic Imbalance in a Male Mouse Model With 5-HT2CR Loss-of-Function.
PubMed5-Hydroxypyrroloindoline Affords Tryptathionine and 2,2′-bis-Indole Peptide Staples: Application to Melanotan-II.
PubMedMelanotan-II reverses memory impairment induced by a short-term HF diet.
PubMedMelanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food.
PubMedTargeting Melanocortin Receptors Using SNAr-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates.
PubMedRelated
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