GORALATIDE (AC-SDKP) — TB-500/TB4

Goralatide is a synthetic tetrapeptide — N-acetyl-Ser-Asp-Lys-Pro — produced for controlled laboratory research into fibrotic and haematopoietic signaling. It corresponds to the N-terminal four residues of thymosin β4 (Tβ4), the 43-amino-acid actin-sequestering protein sold in research markets under the name TB-500. In scientific literature, Ac-SDKP is studied as an endogenous regulatory peptide released from thymosin β4 by prolyl oligopeptidase and meprin-α, and cleared from circulation by the N-domain of angiotensin-converting enzyme. Research frameworks examine its role in collagen synthesis, fibroblast proliferation, inflammatory cell recruitment, and haematopoietic progenitor cell cycling within controlled in vitro and preclinical models.