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Mitochondrial Uncoupler
BAM15 is a synthetic small-molecule mitochondrial protonophore studied in research for its capacity to uncouple oxidative phosphorylation.
This product is intended strictly for laboratory research use within Canada. It is not approved by Health Canada for the diagnosis, treatment, cure, or prevention of any disease. Not for human or veterinary use.
By purchasing, you confirm the material will be used solely for lawful research purposes in accordance with applicable Canadian regulations.
BAM15 is a synthetic small-molecule mitochondrial protonophore studied in research for its capacity to uncouple oxidative phosphorylation.
Experimental models examine its effect on mitochondrial membrane potential and cellular energy metabolism under controlled laboratory conditions.
Third-party tested for purity, ID, quantity.
BAM15 is a mitochondrial uncoupler characterized for its ability to dissipate the proton gradient across the inner mitochondrial membrane without depolarizing the plasma membrane — a selectivity that has made it a tool compound in bioenergetics research.
Studies have evaluated its influence on metabolic rate, insulin sensitivity, and mitochondrial quality-control pathways in preclinical models.
BAM15 was identified during screening for mitochondrial protonophores with improved selectivity over earlier uncouplers such as 2,4-dinitrophenol. Its comparatively favorable profile in cell and animal models established it as a research probe for mitochondrial uncoupling.
Subsequent investigations expanded into metabolic, renal, and oncology research models.
Research into BAM15 centers on mitochondrial uncoupling and cellular energy-metabolism models. Frameworks evaluate membrane-potential dynamics, metabolic regulation, mitophagy, and oxidative signaling under controlled in vitro and preclinical conditions.
No. Eppix Labs products are supplied exclusively for laboratory research. We do not provide dosing, administration, or usage guidance.
Each unit contains the labeled quantity of bam15. Independent third-party analysis verifies purity, identity, and net content per batch.
The unit contains only the research compound. Any laboratory materials required for reconstitution or experimental procedures must be sourced separately.
Duration depends entirely on research design, storage conditions, and laboratory protocol.
Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice
PubMedBAM15 as a mitochondrial uncoupler: a promising therapeutic agent for diverse diseases
PubMedMitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control
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